产品货号：
Z38215
中文名称：
HLA-DRB1抗体
英文名称：
Anti-HLA-DRB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HLA-DRB1 Antibody |
| 指标别名 | DR4;DRB1;DW2.2/DR2.2;HLA DR1B;HLA DRB;HLA DRB1;HLA DRB1*;HLA DRB2;HLA-DRB1;MHC class II antigen DRB1*15;SS1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | HLA-DRB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human HLA-Drb1 Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. |
| 实际分子量 | 30KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HLA class II histocompatibility antigen,DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene.This gene is mapped to 6p21.32.DRB1 encodes the most prevalent beta subunit of HLA-DR.Several alleles of DRB1 (shared epitope alleles) are associated with an increased incidence of rheumatoid arthritis.HLA-DRB1 belongs to the HLA class II beta chain paralogs.The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB),both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins.Class II molecules are expressed in antigen presenting cells (APC:B lymphocytes,dendritic cells,macrophages).The beta chain is approximately 26～28kDa.It is encoded by 6 exons.It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells. |
| Uniprot ID | P01911 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：HLA-DRB1抗体，HLA-DRB1单抗，Anti-HLA-DRB1 Antibody